PROBIOTICS IN THE MANAGEMENT OF PEDIATRIC ATOPIC DERMATITIS

A SYSTEMATIC REVIEW

Authors

  • Thalyta Sales Emery Universidade Federal de Alagoas
  • Aryanne da Silva Nascimento Universidade Federal de Alagoas
  • Larissa de Oliveira Soares Hospital Universitário Pro. Alberto Antunes - HUPAA
  • Selly Martins Soares Universidade Federal de Alagoas
  • Tacy Santana Machado Universidade Federal de Alagoas
  • Myrtis Katille de Assunção Bezerra Universidade Federal de Alagoas

DOI:

https://doi.org/10.17695/rcsne.vol23.n2.p275-285

Keywords:

Atopic dermatitis, Pediatrics, Child, Therapeutics, Probiotics

Abstract

The aim of this study is to analyze what the literature presents regarding the use of probiotics and paraprobiotics as complementary therapies in the treatment of atopic dermatitis (AD) in children and adolescents. A systematic review was carried out of articles indexed in the PubMed, Lilacs, Scielo and Embase databases, which included interventions with probiotics and paraprobiotics. The selection followed the PRISMA strategy, focusing on randomized clinical trials published between 2014 and 2024. Fifty-seven articles were identified, of which 14 met the inclusion criteria. The studies analyzed the SCORAD index (Severity Scoring of Atopic Dermatitis) and indicated a significant reduction in AD symptoms in 53.8% of the clinical trials that used probiotics, with emphasis on the strains Lacticaseibacillus rhamnosus GG, Bifidobacterium bifidum, Lactobacillus sakei proBio65, among others. The results have also shown an improvement in patients' quality of life in some studies and a reduction in the use of medication in others, although the evidence varies depending on the type of probiotic and the context of the treatment. The use of probiotics has potential as a therapeutic adjuvant for AD, but the methodological variability between studies limits definitive conclusions.

Author Biographies

Thalyta Sales Emery, Universidade Federal de Alagoas

Graduanda de nutrição

Aryanne da Silva Nascimento , Universidade Federal de Alagoas

Nutricionista graduada na Universidade Federal de Alagoas

Larissa de Oliveira Soares , Hospital Universitário Pro. Alberto Antunes - HUPAA

Nutricionista materno-infantil - HUPAA

Selly Martins Soares , Universidade Federal de Alagoas

Graduanda de nutrição

Tacy Santana Machado , Universidade Federal de Alagoas

Doutorado em Patologia Vascular e Nutrição pela Universidade Aix-Marseille

Myrtis Katille de Assunção Bezerra, Universidade Federal de Alagoas

Docente adjunto da Fanuldade de nutrição - Universidade Federal de Alagoas

Published

2025-08-29

How to Cite

Sales Emery, T., da Silva Nascimento , A., de Oliveira Soares , L., Martins Soares , S., Santana Machado , T., & de Assunção Bezerra, M. K. (2025). PROBIOTICS IN THE MANAGEMENT OF PEDIATRIC ATOPIC DERMATITIS: A SYSTEMATIC REVIEW. Revista De Ciências Da Saúde Nova Esperança, 23(2), 275–285. https://doi.org/10.17695/rcsne.vol23.n2.p275-285